The tree is used in several cooking preparations in india. The present study is based on the pharmacological activity of aegle marmelos, commonly known as a bael in india. Aegle marmelos fruit extract attenuates helicobacter pylori. The fruit taken in the form of beverage has also great healing potential on account of its mucilage, which forms a coating on the stomach mucosa and thus. Read high performance liquid chromatographic determination of marmelosin and psoralen in bael aegle marmelos l. Phytochemical screening and estimation of total phenolic. Aegle marmelos l currea inhibits the proliferation of transplanted ehrlich ascites carcinoma in mice. Standardization of seed testing procedure for seedling. Aegle marmelos, antioxidant activity, phytoconstituents, 1,1diphyenyl2picryl hydrazyl 1. Introduction the traditional medicinal methods, especially the use of medicinal plants, still play a vital role to cover the basic health needs in the developing countries.
Aegle marmelos which is commonly known as a bael tree belonging to the family rutaceae is the plant that chiefly grows on throughout india. Bhavani 1pg and research department of biochemistry, adhiparasakthi college of arts and science, kalavai 632506, vellore district, tn, india article info abstract article history. Rutaceae, commonly known as bael, bengal quince is a tree of indian origin, well known from pre historic time. Sachin kumar, antioxidant activity of leaf extract of aeglemarmeloscorrea exroxb. This plant is having great potential to cure the disease like diabetes, cholesterol, peptic ulcer, inflammation, diarrhoea, and dysentery, anticancer, cardio protective, anti bacterial. Phytochemistry and medicinal uses of the bael fruit aegle. Tremendous pharmacological values of aegle marmelos. Antidiabetic activity medicinal plant aegle marmelos.
Correa fruit, journal of food science and technology on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Aqueous extract of aegle marmelos leaves was prepared and used for investigation. Haeam unripe fruit using indomethacin and pylorus ligation induced. The full text of this article is available as a pdf 218k. Antimicrobial and antioxidant activity of leaf extracts of. Research article phytochemical evaluation, antimicrobial. Aegle marmelos were kept in a beaker containing ml of %methanolcoveredwithpara lmandthenheatedat. All the parts of this tree including stem, bark, root, leaves, fruit and seeds at all stages of maturity has medicinal virtues and has. Uses, side effects, interactions, dosage, and warning. The leaves, bark, roots, fruits and seeds are used extensively in the indian traditional system of medicine the ayurveda and in various folk medicine to treat myriad ailments. In ayurveda, bael is utilized for its ability to treat an assortment of diseases, including diarrhea, dysentery, and. The present study was aimed to investigate antiulcer activity of methanolic and aqueous extract of aegle marmelos seeds using indomethacin induced ulceration, stressed induced ulceration and pylorus ligation induced ulcerations.
Phytochemical evaluation, antimicrobial activity, and. Aegle marmelos, a plant indigenous to india has been used by the inhabitants of the indian subcontinent for over 5000 years. The plant is widely used in the ayurvedic system of medicine. The ulcer inhibition of aegle marmelos leaves extract 500mgkg 84% was better. The present study was undertaken to findout a scientific validation for the efficacy of aegle marmelos against gastric ulcer.
It grows well in the dry forests of hilly and plain areas. Aegle marmelos leaf extract have significant antiulcer activity in animal models. Biological activities of crude extracts and chemical. The foundation for revitalization of local health traditions frlht, banglore, india assessed threat status of bael aegle marmelos tree as ret rare, endangered and threatened species especially endangered species and importance. Aegle marmelos fruit extract attenuates helicobacter. The antibacterial activity of the leaves of aegle marmelos was reported. Evaluation of antiulcer activity of hydroalcoholic extract. Pharmacodynamics drug receptors and receptor mechanisms pharmacokinetics disposition and metabolism of drugs drug development, the evaluation of new drugs and principles of therapeutics. Bael fruit is recognized for its wide range of medicinal and nutritive properties. Salts on flavonoids in aegle marmelos and moringa oleifera in vitro kavita soni1, asha goswami2 plant tissue culture and biotech. Marmelos a plant of indian origin, with phytopharmacological properties has shown to reduce metabolic disorder such as cholesterol level and blood sugar levels. The antibacterial activity of the different extracts was evaluated by agar well diffusion method. Chemical composition, antimicrobial and antifungal.
Aegle marmelos leaves extract 250mgkg had the least ulcer inhibition effect 67%. Phytochemical analysis on leaf extract of aegle marmelos correa sonu singh, neeta singh abstract aegle marmelos is a subtropical plant which can grow up to an altitude of 1200 m from the sea level. Phytochemical and pharmacological screening of in vivo antiinflammatory activity of aegle marmelos l. Biological activities and volatile constituents of aegle.
Biological activities and volatile constituents of aegle marmelos l. The percentage of sucrose content was measured in gml a. Evaluation of antiulcer activity of hydroalcoholic extract of aegle marmelos l. Aegle marmelos, ethnobotany, pharmacological activities, phytochemistry. A number of chemical constituents and various therapeutic effects of a. Chemical constituents in this plant are flavonoids, tannins, and saponins. Anti ulcer activity of aqueous extract of aegle marmelos leaves on rats. Phytochemical and pharmacological screening of in vivo. It is also found in myanmar, pakistan, bangladesh, burma, nepal, vietnam, laos and cambodia. Effects of ethanolic extract of unripe fruit of aegle. Evaluation of antiulcer activity of moringa oleifera seed. Aegle marmelos or bael is a middle sized slender aromatic armed tree native to india and pakistan.
Essential oil isolated from the leaf has antifungalactivity 14. Evaluation of antioxidant potential and phytochemical. Evaluation of antidiarrhoeal activity of extract from. It is present in sri lanka, tamilnadu, thailand, and malesia as a naturalized species. Evaluation of anti ulcer activity of ethanolic extract of. Aegle marmelos linn is a common plant used to treat many disease conditions in indian traditional systems of medicine. In vitro study was found that the extract was comparable to that of ciprofloxacin and mostly active against the strains of vibrio cholerae, followed by escherichia coli e. The three flavnoids present in the crude extract and enriched in flavnoid fraction are rutin, aspigenin7oglucoside and luteolin7oglucoside. Rutaceae is reported to be important plant in several ethnobotanical and ethnomedicinal studies for its antidiabetic, antiulcer, antiinflammatory, antipyretic, antioxidant and antimicrobial activity 44. Histopathological studies were conducted to support the antiulcer study. It grows mainly within the subhimalayan region kala, 2006.
Protective effect of aegle marmelos fruit in gastrointestinal. Antigenotoxic activity of polyphenolic rich extracts from aegle marmelos l. Pdf aegle marmelos linn is a common plant used to treat many disease conditions in indian traditional systems of medicine. Evaluation of antidiarrhoeal activity of extract from leaves of aegle marmelos hari jagannadha rao g. The plant, though, being highly explored, still lacks sufficient evidences for the best variety possessing the highest degree of medicinal values. The anti ulcer activity of ethanolic extract of aegle marmelos leaves was performed by ethanol induced ulcer model6,7,8. Recently, series of phenylethyl cinnamides, which included new compounds named. In view of these reports, an ethanol extract 50% vv of unriped fruits of aegle marmelos was evaluated for antidiarrhoeal and antiulcer activity in rats with their.
Bhaskara rao molecular and microbiology research laboratory, environmental biotechnology division, school of bio science and technology, vit university, vellore, tamil nadu, india. Materials and methods leaf extraction the leaves of aegle marmelos were collected from in and around areas of thanjavur, tamil nadu, india. Essential oil isolated from the leaf has antifungal activity 8. Hence the present work was planned to investigate the antiulcer activity, claimed traditionally. Extensive studies have been reported on biological activities of various extracts of aegle marmelos including antidiabetic 4, antiulcer 5, anticancer. Correa belonging to family rutaceae is a medium sized deciduous tree indigenous to the indian subcontinent. A study on antimicrobial activity and phytochemical may. Aegle marmelos is a medium sized tree, widely distributed in asia and africa. Haeam unripe fruit using indomethacin and pylorus ligation induced gastric ulcer in wistar rats published may 30, 2019.
Pdf antiulcer activity of aegle marmelos researchgate. Prevention of peptic ulcer by aqueous extract of aegle marmelos. Unorganized tissues medicinally useful plants aegle marmelos and. The results provide promising baseline information for the potential use of this plant as well as some of the fractions in the treatment of microbial diseases. Although aqueous and other leaf extracts of aegle marmelos have been studied for antiulcer activity3,4,5, no reports were found on ethanolic extract of leaves. The compounds luvangetin and pyranocoumarin, isolated from the seeds of a. Antiulcer activity was performed by preparing polyherbal formulation. The present study aims to evaluate the antioxidative and antiulcer effect of methanolic extract of unripe fruit of aegle marmelos. Antidiabetic activity of aegle marmelos and its relationship with its antioxidant properties.
Phytochemical analysis on leaf extract of aegle marmelos. Research article phytochemical evaluation, antimicrobial activity, and determination of bioactive components from leaves of. The purpose of this study was to evaluate and compare the antiinflammatory activity of the aqueous root bark extract of aegle marmelos bilwa in experimental acute and chronic inflammatory animal models. Invitro studies on antidiabetic effect of aegle marmelos. Evaluation of antiulcer activity of hydroalcoholic. Pdf prevention of peptic ulcer by aqueous extract of aegle. Ranitidine 50 mgkg was used as standard antiulcer agent. Aqueous extract of root bark of bilwa was prepared and tested for antiinflammatory activity in albino rats weighing 150280 grams.
Chemical neurotransmission, peripheral autonomic nervous system pharmacology of cholingeric transmission pharmacology of the. Gastric fluid total acidity and free acidity were estimated in pylorus ligated rats. Momordica charantia cucurbitaceaeiscommonlyknownasbittergourd. The tree can thrive under adverse agroclimatic conditions but its commercial cultivation is very limited. The formula contains glycyrrhizia glabra rhizome part 200mg, aegle marmelos l. Chemical constituents in this plant are avonoids, tannins, and saponins antiulcer activity in folk medicine.
New alkaloids from the leaves of aegle marmelos were reported viz. Gastric ulcer was induced by administering ethanol 1 ml200gm. The present investigation revealed that ocimum sanctum exhibited significant antiulcer activity by enhancing antioxidant potential of gastric mucosa thereby reducing mucosal damage. Antidiabetic activity medicinal plant aegle marmelos linn. Antiulcer activity of aegle marmelos linn ncbi nih. Twenty seven components were identified representing 97. Research article phytochemical evaluation, antimicrobial activity, and determination of bioactive components from leaves of aegle marmelos farinamujeeb,preetibajpai,andneelampathak department of biosciences, integral university, kursi road, lucknow, india correspondence should be addressed to neelam pathak. Utilization of bael fruit in daytoday life has a great nutritional, environmental as well as commercial importance. All the animals were fasted for 24 hours before administration of ethanol.
Siddha literatures were obtained from the library of unit of siddha medicine, university of jaffna. Aegle marmelos which is commonly known as a bael tree belonging to the family rutaceae is the plant that chiey grows on throughout india. Evaluation of anti ulcer activity of ethanolic extract of aegle. Department of chemistry, university of alabama in huntsville, huntsville, al 35899 usa. Evaluation of the antiinflammatory activity of aegle. Aegle marmelos linn correa commonly known as bael or bel belonging to the family rutaceae, is a moderate sized, slender and aromatic tree. Aegle marmelos is a plant that belongs to a family of rutaceae.37 1174 740 832 1494 1253 24 1165 732 1080 900 263 801 399 871 834 1527 570 1510 38 1246 923 874 278 1079 795 1074 1412 410 728 1358 422 953 1410 897